Description

Iododifluoroacetyl Fluoride is a highly reactive fluorinated building block characterized by its difluoroacetyl and iodine substituents. This compound is valued for its ability to introduce both fluorine and iodine atoms into target molecules, enabling the synthesis of complex fluorinated intermediates. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for advanced synthetic applications.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of novel fluorinated active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used to create advanced fluorinated pesticides and herbicides, where the introduction of fluorine atoms can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for specialty polymers and advanced materials with unique surface properties and chemical resistance.
• Fluorination Agent: Employed in organic synthesis to selectively incorporate difluoroacetyl and iodine functional groups into complex organic scaffolds.
• Research & Development: A critical tool in medicinal chemistry for structure-activity relationship (SAR) studies and the exploration of new chemical entities.
• Ligand and Catalyst Development: Used in the preparation of novel fluorinated ligands and catalysts for asymmetric synthesis and other specialized reactions.

Basic Information

Product Name	Iododifluoroacetyl Fluoride
CAS No.	44507-93-9
Molecular Formula	C2F3IO
Molecular Weight	239.93 g/mol
Synonyms	Difluoro(iodoacetyl) Fluoride; Iododifluoroacetyl Fluoride; Iodo(difluoroacetyl) Fluoride; 2,2-Difluoro-2-iodoacetyl Fluoride; Acetyl Fluoride, 2,2-difluoro-2-iodo-; Iododifluoroethanoyl Fluoride
EINECS	Contact for details

Quality Control

Our Iododifluoroacetyl Fluoride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including NMR, GC, and IR spectroscopy, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, containers should be kept sealed under an inert atmosphere such as nitrogen or argon. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.