Description

6-Methylcholesterol is a specific methylated derivative of cholesterol, a key sterol in biological systems. This compound is valued as a high-purity reference standard and a critical intermediate in advanced pharmaceutical and biochemical research. It is essential for scientists and manufacturers in the pharmaceutical, life sciences, and fine chemical sectors who require precise, well-characterized sterols for analytical method development, metabolic studies, and the synthesis of more complex bioactive molecules.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, purity assessment, and quantification of sterols in drug substances and finished products via HPLC, GC, or LC-MS.
• Biochemical Research: Serves as a crucial intermediate or substrate in studies of cholesterol metabolism, enzyme activity assays, and the investigation of lipid membrane properties.
• Fine Chemical Synthesis: Acts as a key building block for the synthesis of more complex steroid derivatives, drug candidates, and labeled compounds for tracer studies.
• Analytical Method Development: Employed in laboratories to develop, validate, and calibrate analytical methods for sterol analysis in various matrices, ensuring accuracy and regulatory compliance.
• Academic & Industrial R&D: Utilized in fundamental research exploring the structure-activity relationships of sterols and their role in biological pathways.

Basic Information

Product Name	6-Methylcholesterol
CAS No.	43217-66-9
Molecular Formula	C28H48O
Molecular Weight	400.68 g/mol
Synonyms	6α-Methylcholesterol; (3β)-Cholest-5-en-3-ol, 6-methyl-; 6-Methylcholest-5-en-3β-ol; 6-Methyl-δ5-cholesterol; NSC 69863
EINECS	Contact for details

Quality Control

Our 6-Methylcholesterol is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity determination by chromatographic techniques. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results against agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize the risk of oxidation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Specification available upon request
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.