Description

Thymidine Bromohydrin CAS NO 43179-28-8 is a specialized nucleoside derivative, a key brominated intermediate in organic synthesis. This compound is valued for its role in introducing functional complexity into nucleoside scaffolds, enabling the development of novel pharmaceutical agents and biochemical probes. It is primarily utilized by research institutions and pharmaceutical companies engaged in antiviral drug discovery, nucleotide chemistry, and the synthesis of modified nucleic acids.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used in the study of DNA structure, function, and the development of nucleotide-based probes.
• Organic Synthesis: Serves as a versatile intermediate for introducing bromohydrin functionality into complex molecular architectures.
• Antiviral Drug Development: Particularly relevant in the research and development pipeline for modified nucleoside reverse transcriptase inhibitors.
• Academic Research: Employed in university and institutional labs for investigating nucleoside chemistry and reaction mechanisms.

Basic Information

Product Name	Thymidine Bromohydrin
CAS No.	43179-28-8
Molecular Formula	C10H15BrN2O5
Molecular Weight	323.14 g/mol
Synonyms	1-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-(2-bromo-1-hydroxyethyl)uracil; 5-(2-Bromo-1-hydroxyethyl)-2'-deoxyuridine; 5-(2-Bromo-1-hydroxyethyl)thymidine; Bromohydrin of 5-Hydroxymethyl-2'-deoxyuridine; 5-(Bromohydroxyethyl)-2'-deoxyuridine; 2'-Deoxy-5-(2-bromo-1-hydroxyethyl)uridine; Thymidine, 5-(2-bromo-1-hydroxyethyl)-
EINECS	Contact for details

Quality Control

Our Thymidine Bromohydrin is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We are committed to meeting the exacting standards required for pharmaceutical intermediates and advanced research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.