Description

1H-Indene-2-Carbonyl Chloride (9Ci) is a versatile and highly reactive organic intermediate, specifically an acid chloride derivative of indene. Its core value proposition lies in its ability to act as a key building block for the synthesis of more complex molecules, enabling the introduction of the indene-carbonyl moiety into target structures. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require high-purity intermediates for drug discovery and specialty polymer development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with indene-based scaffolds.
• Organic Synthesis Building Block: Used in amidation and esterification reactions to create novel amides, esters, and peptides for research and development.
• Material Science Research: Employed in the development of specialty polymers, dyes, and photoactive materials due to its conjugated indene structure.
• Agrochemical Synthesis: Acts as an intermediate in the creation of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Utilized for synthesizing specialized ligands for metal-organic frameworks (MOFs) and asymmetric catalysis.

Basic Information

Product Name	1H-Indene-2-Carbonyl Chloride (9Ci)
CAS No.	43073-37-6
Molecular Formula	C10H7ClO
Molecular Weight	178.62 g/mol
Synonyms	1H-Indene-2-carbonyl chloride; 2-Indenecarbonyl chloride; Indene-2-carbonyl chloride; 2-Carboxyindene chloride; 1H-Indene-2-carboxylic acid chloride; 43073-37-6; 2-Indenoyl chloride
EINECS	Contact for details

Quality Control

Our 1H-Indene-2-Carbonyl Chloride (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles for pharmaceutical-grade intermediates, ensuring compliance with global regulatory expectations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.