Description

4-Thiazolecarbonylchloride,2-Nitro-(9Ci) is a specialized heterocyclic building block and reactive intermediate of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a reactive acid chloride group and a nitro-substituted thiazole ring, enabling precise molecular construction. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel thiazole-containing drug candidates, particularly for antimicrobial, anti-inflammatory, or kinase inhibitor applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides that leverage the bioactive thiazole scaffold.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in catalysis or metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, dyes, or photoactive compounds due to its electron-withdrawing nitro group.
• Custom Chemical Synthesis: Provides a versatile handle for amide bond formation and further functionalization in contract research and fine chemical production.

Basic Information

Product Name	4-Thiazolecarbonylchloride,2-Nitro-(9Ci)
CAS No.	43029-01-2
Molecular Formula	C4H3ClN2O3S
Molecular Weight	194.60 g/mol
Synonyms	2-Nitro-4-thiazolecarbonyl chloride; 2-Nitrothiazole-4-carbonyl chloride; 2-Nitro-1,3-thiazole-4-carbonyl chloride; 4-Thiazolecarbonyl chloride, 2-nitro-; 2-Nitro-4-thiazole carboxylic acid chloride; 2-Nitrothiazole-4-carboxylic acid chloride; 2-Nitro-1,3-thiazole-4-carboxylic acid chloride; 2-Nitro-4-carboxythiazole chloride
EINECS	Contact for details

Quality Control

Our 4-Thiazolecarbonylchloride,2-Nitro-(9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.