Description

2,4-Dihydroxyestrone is a specific, hydroxylated metabolite of the primary estrogen, estrone, with the CAS registry number 42979-86-2. This compound is of significant interest in biochemical and pharmaceutical research for its role in estrogen metabolism and its potential biological activity. It serves as a critical reference standard and intermediate for researchers and developers in the life sciences sector. Target users include analytical laboratories, pharmaceutical R&D departments, and academic institutions focused on endocrinology, cancer research, and metabolic studies.

Application

• Biochemical Research Standard: Used as a high-purity reference material for calibrating analytical instruments like HPLC and LC-MS in studies of estrogen metabolism.
• Pharmaceutical Intermediate: Serves as a key synthetic building block in the development of novel therapeutic agents and hormone analogs.
• Clinical Diagnostics: Employed in the development and validation of diagnostic assays to quantify estrogen metabolites in biological samples.
• Metabolic Pathway Studies: Essential for in-vitro and in-vivo research investigating the enzymatic pathways and biological effects of estrogen derivatives.
• Academic Research: A vital tool for universities and research institutes conducting fundamental studies in endocrinology, oncology, and toxicology.
• Quality Control: Acts as a system suitability standard in pharmaceutical quality control laboratories to ensure the accuracy of estrogen-related analyses.

Basic Information

Product Name	2,4-Dihydroxyestrone
CAS No.	42979-86-2
Molecular Formula	C18H22O4
Molecular Weight	302.37 g/mol
Synonyms	2,4-Dihydroxyestrone; 1,3,5(10)-Estratrien-2,4-diol-17-one; Estra-1,3,5(10)-triene-2,4-diol-17-one; 2,4-Dihydroxy-17-oxoestra-1,3,5(10)-triene; 2,4-Dihydroxyestra-1,3,5(10)-trien-17-one; 2,4-Dihydroxy-E1; 2,4-DiOH-E1
EINECS	Contact for details

Quality Control

Our 2,4-Dihydroxyestrone is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods (IR, NMR) for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.