Description

(3β,5β,7α,12α)-3-(Formyloxy)-7,12-Dihydroxycholan-24-Oic Acid Methyl Ester is a key cholic acid derivative and a crucial synthetic intermediate in the production of high-value pharmaceutical compounds. Its precise stereochemistry and functional groups make it an essential building block for researchers and manufacturers developing advanced therapeutic agents. This compound is primarily utilized by the pharmaceutical and fine chemical industries for the synthesis of novel drug candidates and reference standards.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of ursodeoxycholic acid (UDCA) and other therapeutic bile acids.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key chiral building block for the development of hepatoprotective and cholesterol-lowering drugs.
• Biochemical Research: Used as a standard or reagent in metabolic pathway studies and enzyme inhibition research related to bile acid metabolism.
• Fine Chemical Production: Employed in the manufacture of specialized surfactants, detergents, and other value-added chemical products derived from steroid frameworks.
• Reference Standard: Provides a high-purity compound for analytical method development, validation, and quality control in regulatory and R&D laboratories.

Basic Information

Product Name	(3β,5β,7α,12α)-3-(Formyloxy)-7,12-Dihydroxycholan-24-Oic Acid Methyl Ester
CAS No.	42921-40-4
Molecular Formula	C₂₆H₄₂O₇
Molecular Weight	466.61 g/mol
Synonyms	Methyl 3α-formyloxy-7α,12α-dihydroxy-5β-cholan-24-oate; 3α-Formyloxy-7α,12α-dihydroxy-5β-cholan-24-oic Acid Methyl Ester; 7α,12α-Dihydroxy-3α-formyloxy-5β-cholan-24-oic Acid Methyl Ester; Methyl 3-formyloxy-7,12-dihydroxycholan-24-oate; 3-Formyloxy-7,12-dihydroxycholan-24-oic Acid Methyl Ester; UDCA Intermediate; Ursodeoxycholic Acid Intermediate
EINECS	Contact for details

Quality Control

Our (3β,5β,7α,12α)-3-(Formyloxy)-7,12-Dihydroxycholan-24-Oic Acid Methyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, and is supplied with a detailed Certificate of Analysis (COA) to confirm identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.