Description

Uridine, 2',3'-Didehydro-2',3'-Dideoxy-, 5'-Acetate is a chemically modified nucleoside analog, a key intermediate in the synthesis of specialized antiviral and pharmaceutical compounds. This product matters for its role in developing nucleoside reverse transcriptase inhibitors (NRTIs), which are critical in antiviral research and therapeutic development. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers focused on antiviral drug discovery and nucleotide chemistry.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of advanced nucleoside-based antiviral agents.
• Antiviral Research: Used in the research and development of novel nucleoside reverse transcriptase inhibitors (NRTIs) for virology studies.
• Biochemical Research: Serves as a modified substrate or inhibitor in enzymatic studies involving polymerases and other nucleotide-processing enzymes.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for high-value specialty chemicals.
• Reference Standard: Utilized as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	Uridine, 2',3'-Didehydro-2',3'-Dideoxy-, 5'-Acetate
CAS No.	42867-74-3
Molecular Formula	C11H12N2O5
Molecular Weight	252.22 g/mol
Synonyms	2',3'-Didehydro-2',3'-Dideoxyuridine 5'-Acetate; d4U 5'-Acetate; 2',3'-Dideoxy-2',3'-didehydrouridine 5'-acetate; 1-[(2R,5S)-5-(Acetyloxy)-2,5-dihydrofuran-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione; 5'-O-Acetyl-2',3'-didehydro-2',3'-dideoxyuridine; NSC 615985; Uridine, 2',3'-didehydro-2',3'-dideoxy-, 5'-acetate
EINECS	Contact for details

Quality Control

Our Uridine, 2',3'-Didehydro-2',3'-Dideoxy-, 5'-Acetate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with full batch traceability are provided.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.