Description

2,3,5-Triiodo-Benzoyl Chloride is a highly functionalized aromatic acid chloride derivative, characterized by the presence of three iodine atoms on the benzoyl chloride core. This compound is a critical high-purity synthetic intermediate used in the preparation of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in thyroid hormone analogs and X-ray contrast media agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of monomers for advanced polymers and liquid crystals due to its heavy atom substitution.
• Diagnostic Agent Development: Utilized in the research phase for developing iodine-containing compounds used in medical imaging.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2,3,5-Triiodo-Benzoyl Chloride
CAS No.	42860-33-3
Molecular Formula	C7H2ClI3O
Molecular Weight	513.26 g/mol
Synonyms	2,3,5-Triiodobenzoyl chloride; Benzoyl chloride, 2,3,5-triiodo-; 2,3,5-Triiodobenzoic acid chloride; Triiodobenzoyl chloride; TIB-Cl; 42860-33-3 (CAS); 2,3,5-Triiodo-benzoic acid chloride
EINECS	Contact for details

Quality Control

Our 2,3,5-Triiodo-Benzoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Solubility	Soluble in common organic solvents (e.g., DCM, THF, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.