Description

6-Nitroveratryl Chloroformate is a specialized chemical reagent primarily used as a photolabile protecting group for amines and alcohols. This compound matters for its critical role in the synthesis of photoremovable protecting groups (PPGs), enabling precise spatial and temporal control in advanced chemical and biochemical applications. It is needed by research institutions and pharmaceutical companies engaged in peptide synthesis, prodrug development, and the creation of light-sensitive materials and caged compounds.

Application

• As a key reagent for introducing the 6-nitroveratryloxycarbonyl (NVOC) protecting group in solid-phase peptide synthesis (SPPS).
• In the preparation of photolabile "caged" compounds for biological studies, allowing for the controlled release of bioactive molecules upon irradiation.
• For the protection of amino groups in the synthesis of complex organic molecules and natural products, where a light-deprotection strategy is advantageous.
• In material science for the development of photo-patternable polymers and surfaces with light-responsive properties.
• As a building block in prodrug design, facilitating targeted drug activation using specific wavelengths of light.
• Utilized in biochemical research for labeling and modifying biomolecules with a cleavable linker for downstream analysis.

Basic Information

Product Name	6-Nitroveratryl Chloroformate
CAS No.	42855-00-5
Molecular Formula	C10H10ClNO6
Molecular Weight	275.64 g/mol
Synonyms	6-Nitroveratryl Chloroformate; 4,5-Dimethoxy-2-nitrobenzyl Chloroformate; NVOC-Chloride; 2-Nitroveratryl Chloroformate; (4,5-Dimethoxy-2-nitrophenyl)methyl Chloroformate; α-Chloroformate of 4,5-Dimethoxy-2-nitrobenzyl Alcohol; 6-Nitroveratrylcarbonyl Chloride (common misnomer); NVOC-Cl
EINECS	Contact for details

Quality Control

Our 6-Nitroveratryl Chloroformate is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.