Description

Cytidine, 3'-Acetate CAS NO 42829-52-7 is a chemically modified nucleoside derivative where an acetyl group is esterified to the 3'-hydroxyl position of the ribose sugar. This modification is crucial for protecting specific hydroxyl groups during oligonucleotide synthesis, enabling the precise construction of RNA and DNA analogs. It serves as a critical building block and key intermediate for pharmaceutical research, diagnostic development, and advanced biochemical studies.

Application

• Oligonucleotide Synthesis: As a protected monomer for solid-phase synthesis of RNA and antisense oligonucleotides.
• Pharmaceutical Intermediates: Key starting material in the development of nucleoside-based antiviral and anticancer prodrugs.
• Biochemical Research: Used in enzymatic studies and as a substrate for investigating nucleotide-modifying enzymes.
• Diagnostic Probe Development: Essential for creating labeled probes and primers used in PCR and molecular diagnostics.
• Academic & Industrial R&D: Fundamental reagent for exploring nucleic acid chemistry and developing novel therapeutic modalities.

Basic Information

Product Name	Cytidine, 3'-Acetate
CAS No.	42829-52-7
Molecular Formula	C12H15N3O6
Molecular Weight	297.26 g/mol
Synonyms	3'-O-Acetylcytidine; Cytidine 3'-acetate; 1-((2R,3R,4R,5R)-3-Acetoxy-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-aminopyrimidin-2(1H)-one; 3'-Acetylcytidine; N4-Amino-1-(3-O-acetyl-β-D-ribofuranosyl)-2(1H)-pyrimidinone; 2(1H)-Pyrimidinone, 4-amino-1-(3-O-acetyl-β-D-ribofuranosyl)-
EINECS	Contact for details

Quality Control

Our Cytidine, 3'-Acetate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.