Description

2-Bromo-3-Phenylpropanoyl Chloride is a versatile and highly reactive organic building block, primarily used as an acylating agent in advanced synthetic chemistry. Its core value proposition lies in enabling the efficient introduction of the 2-bromo-3-phenylpropanoyl moiety, a key intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a critical precursor for the development of active pharmaceutical ingredients (APIs) and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of protease inhibitors and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific phenylpropanoate structures.
• Peptide Chemistry: Employed as an acylating agent for the modification of amino acids and peptides, facilitating the creation of custom peptide derivatives.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialized polymers with unique thermal or mechanical properties.
• Ligand and Catalyst Development: Utilized in organic and organometallic chemistry to synthesize novel chiral ligands and catalytic complexes.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical suppliers and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Item	Details
Product Name	2-Bromo-3-Phenylpropanoyl Chloride
CAS No.	42762-86-7
Molecular Formula	C9H8BrClO
Molecular Weight	247.52 g/mol
Synonyms	2-Bromo-3-phenylpropionyl chloride; 3-Phenyl-2-bromopropanoyl chloride; (2-Bromo-3-phenylpropanoyl) chloride; β-Bromohydrocinnamoyl chloride; NSC 163082; 2-Bromo-3-phenyl-1-oxopropan-1-yl chloride; α-Bromo-β-phenylpropionyl chloride
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Phenylpropanoyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of research and industrial synthesis. Certificates of Analysis (COA) with full traceability are provided for every shipment, guaranteeing reliable performance and consistency in your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and separated from bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.