Description

o-Isopropoxyphenyl Chloroformate is a specialized organic reagent belonging to the class of chloroformates. This compound serves as a versatile building block in organic synthesis, primarily valued for its role as an efficient coupling agent and protecting group intermediate. It is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to introduce the o-isopropoxyphenyl moiety or create carbonate linkages under controlled conditions.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing prodrugs or modifying drug molecules to enhance bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the isopropoxyphenyl group imparts specific biological activity.
• Polymer Chemistry: Acts as a monomer or chain modifier in the synthesis of specialty polycarbonates and other functional polymers.
• Peptide & Protein Research: Employed as a coupling agent in peptide synthesis and for the modification of amino acids or proteins.
• Chemical Derivatization: Useful for analytical chemistry applications, such as derivatizing compounds for gas chromatography (GC) or liquid chromatography (LC) analysis to improve detection.
• Material Science: Intermediate in the development of advanced materials, including liquid crystals and organic electronic components.

Basic Information

Product Name	o-Isopropoxyphenyl Chloroformate
CAS No.	42572-19-0
Molecular Formula	C10H11ClO3
Molecular Weight	214.65 g/mol
Synonyms	2-Isopropoxyphenyl Chloroformate; (2-Isopropoxyphenyl) Carbonochloridate; o-Isopropoxy Phenyl Chloroformate; Chloroformic Acid 2-Isopropoxyphenyl Ester; 2-(1-Methylethoxy)phenyl Chloroformate; Isopropoxyphenyl Chloroformate; Carbonochloridic Acid, 2-(1-Methylethoxy)phenyl Ester
EINECS	Contact for details

Quality Control

Our o-Isopropoxyphenyl Chloroformate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.18 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.