Description

1H-Benzimidazole,5-Isothiocyanato-(9Ci) is a specialized heterocyclic organic compound featuring a reactive isothiocyanate group attached to a benzimidazole core. This molecular architecture makes it a versatile and critical building block for the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially those targeting specific enzyme pathways.
• Agrochemical Research: Used in developing novel fungicides, herbicides, or plant growth regulators due to its bioactive benzimidazole scaffold.
• Bioconjugation & Probe Synthesis: The reactive isothiocyanate group allows for covalent attachment to amines in proteins, peptides, or other biomolecules, useful for creating fluorescent probes or affinity labels.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or chemical resistance properties.
• Chemical Biology: Employed in activity-based protein profiling (ABPP) and other chemoproteomic applications to study enzyme function and discover new targets.

Basic Information

Product Name	1H-Benzimidazole,5-Isothiocyanato-(9Ci)
CAS No.	42517-55-5
Molecular Formula	C8H5N3S
Molecular Weight	175.21 g/mol
Synonyms	5-Isothiocyanato-1H-benzimidazole; 5-Isothiocyanatobenzimidazole; 1H-Benzimidazole-5-isothiocyanate; Benzimidazole-5-isothiocyanate; NSC 401565; 5-Isothiocyanato-benzimidazole; 5-Benzimidazole isothiocyanate
EINECS	Contact for details

Quality Control

Our production of 1H-Benzimidazole,5-Isothiocyanato-(9Ci) adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques, and a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided. We support cGMP compliance for applications requiring rigorous documentation and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Contact for higher grades)
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.