Description

2-Aminopurine Riboside-3',5'-Cyclic Monophosphate Sodium Salt is a chemically modified nucleotide analog, specifically a sodium salt of a cyclic AMP derivative. This compound is a critical biochemical tool for studying cyclic nucleotide signaling pathways, particularly as a fluorescent analog of cAMP for probing enzyme kinetics and binding interactions. It is primarily utilized by researchers and developers in pharmaceutical R&D, academic biochemistry, and diagnostic assay development for investigating phosphodiesterase activity and protein kinase A (PKA) function.

Application

• Biochemical Research: As a fluorescent probe and substrate analog for studying cyclic AMP-dependent enzymes, including phosphodiesterases (PDEs) and protein kinases.
• Enzyme Assay Development: Used in high-throughput screening (HTS) assays to identify and characterize potential PDE inhibitors for drug discovery.
• Cell Signaling Studies: Employed in cellular systems to monitor real-time changes in cAMP dynamics due to its fluorescent properties.
• Diagnostic Reagent Manufacturing: A key component in the formulation of specialized diagnostic kits for research and clinical analysis of nucleotide-related pathways.
• Pharmaceutical R&D: Serves as a reference standard and a tool compound in the development of therapeutics targeting cardiovascular, neurological, and inflammatory diseases.

Basic Information

Product Name	2-Aminopurine Riboside-3',5'-Cyclic Monophosphate Sodium Salt
CAS No.	42467-66-3
Molecular Formula	C11H12N5NaO7P
Molecular Weight	380.21 g/mol
Synonyms	2-Aminopurine Riboside 3',5'-Cyclic Monophosphate Sodium Salt; 2-AP-cAMP Sodium Salt; 2-Aminopurine Cyclic AMP Sodium Salt; 2-Aminopurine-9-β-D-ribofuranosyl 3',5'-Cyclic Monophosphate Sodium Salt; 2-Aminopurine-9-β-D-ribofuranosyl 3',5'-Cyclic Phosphate Sodium Salt; 2-AP-riboside 3',5'-cyclic monophosphate sodium salt; 2-Aminopurine-9-β-D-ribofuranosyl cyclic 3',5'-(hydrogen phosphate) sodium salt
EINECS	Contact for details

Quality Control

Our 2-Aminopurine Riboside-3',5'-Cyclic Monophosphate Sodium Salt is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 standards, and our quality systems support development under cGMP guidelines for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep desiccated under an inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.