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Iodocholesterol CAS NO 42220-21-3
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CAS No.:42220-21-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Iodocholesterol is a halogenated derivative of cholesterol, a key intermediate in organic synthesis and biochemical research. This compound is valued for its role as a versatile building block in the preparation of labeled steroids and other complex molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in steroid chemistry, radiopharmaceutical development, and metabolic pathway studies.
Application
- Pharmaceutical Intermediate: A crucial precursor in the synthesis of iodinated steroid drugs and diagnostic agents.
- Biochemical Research: Used as a substrate or intermediate in studies of cholesterol metabolism, enzyme activity, and receptor binding assays.
- Radiopharmaceuticals: Serves as a starting material for the preparation of radioiodinated cholesterol analogs used in medical imaging.
- Organic Synthesis: Acts as a versatile building block for introducing the cholesterol skeleton into more complex molecular architectures.
- Reference Standard: Employed as an analytical standard in chromatography (HPLC, GC) for quality control and method development.
Basic Information
| Product Name | Iodocholesterol |
| CAS No. | 42220-21-3 |
| Molecular Formula | C27H45IO |
| Molecular Weight | 512.56 g/mol |
| Synonyms | 3β-Iodo-5-cholestene; Cholest-5-en-3β-ol, 3-iodo-; 3-Iodocholest-5-en-3β-ol; Iodocholest-5-en-3β-ol; 3β-Iodocholest-5-ene; 5-Cholesten-3β-ol, 3-iodo-; Iodocholestene |
| EINECS | Contact for details |
Quality Control
Our Iodocholesterol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 1.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Why choose US
Trusted Manufacturer
With our own production facilities, we ensure consistent quality, reliable supply, and full traceability.
Rigorous Quality Assurance
Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
Advanced R&D Expertise
Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.






