Description

2-Propenoyl Chloride, 2-Bromo- CAS NO 41965-71-3 is a highly reactive halogenated acryloyl chloride derivative, serving as a critical building block for introducing the 2-bromoacryloyl functional group. Its value lies in enabling precise synthetic modifications in advanced organic and polymer chemistry, where its dual reactive sites offer versatile coupling possibilities. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to develop novel active ingredients or functional materials.

Application

• Pharmaceutical Intermediates: Key synthon for the preparation of targeted small molecule drugs and protease inhibitors.
• Agrochemical Synthesis: Used in constructing novel herbicide and fungicide molecules with enhanced activity.
• Polymer Science: Serves as a functional monomer or cross-linking agent for creating specialty polymers with unique thermal or mechanical properties.
• Material Science: Employed in surface modification and the synthesis of advanced organic frameworks or coatings.
• Chemical Research: A versatile reagent for Michael addition reactions, nucleophilic substitutions, and other C-C/C-X bond-forming transformations in academic and industrial R&D.
• Ligand and Catalyst Development: Useful for synthesizing novel chelating ligands or organocatalysts.

Basic Information

Product Name	2-Propenoyl Chloride, 2-Bromo-
CAS No.	41965-71-3
Molecular Formula	C3H2BrClO
Molecular Weight	169.40 g/mol
Synonyms	2-Bromoacryloyl Chloride; 2-Bromo-2-propenoyl Chloride; (2-Bromoethenyl)carbonyl Chloride; 2-Bromoacrylic Acid Chloride; Bromoacryloyl Chloride; NSC 163063; α-Bromoacryloyl Chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Bromoacryloyl Chloride is produced and tested under stringent quality management protocols to ensure consistency and reliability for your synthetic processes. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data. Our quality systems are designed to support applications requiring high-purity intermediates, including cGMP manufacturing for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place, preferably at 2-8°C. This product is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent hydrolysis. Isolate from incompatible materials such as strong bases, oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.