Description

Tributyryladenosine Monophosphate is a chemically modified nucleotide analog where the hydroxyl groups of the ribose moiety are esterified with butyryl groups. This modification enhances its lipophilicity and cell membrane permeability, making it a valuable biochemical tool for studying intracellular signaling pathways. It is primarily utilized in life science research and pharmaceutical development. This product is essential for researchers and manufacturers focused on nucleotide metabolism, kinase activity, and the development of prodrug strategies.

Application

• Biochemical Research: Used as a cell-permeable precursor for adenosine monophosphate (AMP) in studies of intracellular energy metabolism and signal transduction.
• Enzyme Substrate: Serves as a substrate analog for investigating the activity and inhibition of specific kinases and phosphodiesterases.
• Pharmaceutical Intermediates: Acts as a key synthetic intermediate in the development of nucleotide-based prodrugs and therapeutic agents.
• Metabolic Pathway Analysis: Employed in tracer studies to elucidate AMP-related metabolic fluxes and regulatory mechanisms within cells.
• Cell Signaling Studies: Useful for modulating AMP-activated protein kinase (AMPK) pathways in experimental models to study cellular stress responses.

Basic Information

Product Name	Tributyryladenosine Monophosphate
CAS No.	41935-05-1
Molecular Formula	C22H34N5O8P
Molecular Weight	551.51 g/mol
Synonyms	Adenosine 5'-Monophosphate Tributyrate; N6-Tributyryl-AMP; 5'-O-Tributyryl Adenosine Monophosphate; Tributyryl-AMP; AMP Tributyrate; Adenosine 5'-(dihydrogen phosphate) 2',3',5'-tributyrate; Butyryl Adenylate Ester
EINECS	Contact for details

Quality Control

Our Tributyryladenosine Monophosphate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.