Description

2-(3-Chlorophenyl)Acetyl Chloride is a versatile and reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 2-(3-chlorophenyl)acetyl moiety into target molecules, enabling the construction of complex chemical architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the chlorophenyl group enhances biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Employed in the synthesis of specialty polymers and resins, including photoactive materials and high-performance engineering plastics.
• Dyestuff and Pigment Manufacturing: Acts as an intermediate for producing complex organic dyes and pigments with specific color fastness and stability properties.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories exploring novel chemical entities and reaction pathways.

Basic Information

Product Name	2-(3-Chlorophenyl)Acetyl Chloride
CAS No.	41904-39-6
Molecular Formula	C8H6Cl2O
Molecular Weight	189.04 g/mol
Synonyms	3-Chlorophenacyl Chloride; (3-Chlorophenyl)acetyl Chloride; 2-Chloro-1-(3-chlorophenyl)ethanone; 3-Chloro-ω-chloroacetophenone; m-Chlorophenacyl Chloride; NSC 408950; α-Chloro-3-chloroacetophenone; 3'-Chlorophenacyl Chloride
EINECS	Contact for details

Quality Control

Our 2-(3-Chlorophenyl)Acetyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at 2-8°C (refrigerated) or as specified for specific grades. This product is hygroscopic (moisture-sensitive) and a strong acid/organic solvent; keep away from moisture, heat, and incompatible materials such as bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.