Description

Triethyl 3-Methyl-4-Phosphonocrotonate is a high-purity organophosphorus compound, specifically a phosphonate ester, valued for its role as a versatile synthetic intermediate in advanced organic synthesis. Its primary commercial significance lies in its utility for constructing complex molecular frameworks, particularly in the synthesis of pharmaceuticals and specialty chemicals. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality building blocks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing phosphonate or modified amino acid motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, plant growth regulators, and other crop protection agents.
• Horner-Wadsworth-Emmons (HWE) Reaction Reagent: Serves as a stabilized phosphonate ylide precursor for the stereoselective formation of α,β-unsaturated esters (olefination).
• Ligand and Catalyst Precursor: Employed in the development of novel organophosphorus ligands for metal-catalyzed reactions.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique properties.
• Academic & Industrial R&D: A critical reagent for methodological development and exploratory synthesis in organic chemistry laboratories.

Basic Information

Product Name	Triethyl 3-Methyl-4-Phosphonocrotonate
CAS No.	41891-54-7
Molecular Formula	C12H23O5P
Molecular Weight	278.28 g/mol
Synonyms	Triethyl (3-Methyl-4-phosphonocrotonate); Diethyl (1-Ethoxycarbonyl-2-methylvinyl)phosphonate; (1-Ethoxycarbonyl-2-methylvinyl)phosphonic Acid Diethyl Ester; 3-Methyl-4-(diethoxyphosphinyl)-2-butenoic Acid Ethyl Ester; Diethyl 1-(Ethoxycarbonyl)-2-methylvinylphosphonate; Phosphonocrotonic Acid, 3-Methyl-, Triethyl Ester; Crotonic acid, 3-methyl-4-phosphono-, triethyl ester
EINECS	Contact for details

Quality Control

Our Triethyl 3-Methyl-4-Phosphonocrotonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.