Description

2H-Chromene-3-Carbonyl Chloride is a versatile and highly reactive organic intermediate, essential for constructing complex molecular architectures. Its core value lies in its carbonyl chloride functional group, which readily undergoes acylation reactions to form amides, esters, and other derivatives. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key building block for the synthesis of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those with chromene or coumarin-based scaffolds for therapeutic applications.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the chromene core can contribute to biological activity.
• Fine Chemical Production: Serves as a building block for dyes, pigments, and functional materials that require the chromene structure.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D labs for exploring new acylation reactions and heterocyclic chemistry.
• Material Science: Potential use in the synthesis of monomers or precursors for advanced polymers and coatings with specific optical properties.

Basic Information

Product Name	2H-Chromene-3-Carbonyl Chloride
CAS No.	41873-72-7
Molecular Formula	C10H7ClO2
Molecular Weight	194.61 g/mol
Synonyms	3-Chlorocarbonyl-2H-chromene; 2H-1-Benzopyran-3-carbonyl chloride; Chromene-3-carbonyl chloride; 2H-Chromen-3-carbonyl chloride; 3-Chlorocarbonyl-2H-1-benzopyran; 2H-1-Benzopyran-3-carboxylic acid chloride; 3-Carboxy-2H-chromene chloride; Coumarin-3-carbonyl chloride (related structure)
EINECS	Contact for details

Quality Control

Our 2H-Chromene-3-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and reactive nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) and at a controlled room temperature (15-25°C) to maintain stability and prevent hydrolysis.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.