Description

(2S,4Aβ,8Aβ,10Aα)-7α-(Acetyloxy)-3,4,4A,4B,5,6,7,8,8A,9,10,10A-Dodecahydro-2β,4Bα-Dimethyl-1(2H)-Phenanthrenone is a high-purity, complex diterpenoid derivative with a defined stereochemistry, making it a valuable advanced pharmaceutical intermediate and research chemical. Its intricate structure serves as a critical building block for the synthesis of novel bioactive compounds, particularly in steroid and terpenoid chemistry. This compound is essential for R&D laboratories and pharmaceutical manufacturers engaged in developing new therapeutic agents and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel steroid-mimetic drugs and other bioactive molecules.
• Organic Synthesis Research: Used in academic and industrial laboratories to explore new synthetic pathways for complex polycyclic compounds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical chemistry.
• Biochemical Research: Investigated for its potential biological activity and interactions with enzymes or receptors in pharmacological studies.
• Chemical Library Building: Employed in the construction of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	(2S,4Aβ,8Aβ,10Aα)-7α-(Acetyloxy)-3,4,4A,4B,5,6,7,8,8A,9,10,10A-Dodecahydro-2β,4Bα-Dimethyl-1(2H)-Phenanthrenone
CAS No.	41853-35-4
Molecular Formula	C20H30O3
Molecular Weight	318.45 g/mol
Synonyms	7α-Acetoxy-4b,10a-dimethyl-2,3,4,4a,4b,5,6,7,8,8a,9,10-dodecahydro-1(2H)-phenanthrenone; 7α-Acetoxy-4b,10a-dimethyl-1-oxo-1,2,3,4,4a,4b,5,6,7,8,8a,9,10,10a-tetradecahydrophenanthrene; (2S,4aR,8aR,10aS)-7α-Acetoxy-4b,10a-dimethyl-2,3,4,4a,4b,5,6,7,8,8a,9,10-dodecahydro-1(2H)-phenanthrenone; 7α-Acetoxy-4b,10a-dimethyl-1-oxo-1,2,3,4,4a,4b,5,6,7,8,8a,9,10,10a-tetradecahydrophenanthrene; 7α-Acetoxy-4b,10a-dimethyl-1-oxo-1,2,3,4,4a,4b,5,6,7,8,8a,9,10,10a-tetradecahydrophenanthrene (2S,4aR,8aR,10aS)-; 7α-Acetoxy-4b,10a-dimethyl-1-oxo-1,2,3,4,4a,4b,5,6,7,8,8a,9,10,10a-tetradecahydrophenanthrene (2S,4aR,8aR,10aS)-form
EINECS	Contact for details

Quality Control

Our (2S,4Aβ,8Aβ,10Aα)-7α-(Acetyloxy)-3,4,4A,4B,5,6,7,8,8A,9,10,10A-Dodecahydro-2β,4Bα-Dimethyl-1(2H)-Phenanthrenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent stereochemical integrity, meeting the stringent requirements for advanced research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.