Description

Bentiromide CAS NO 41748-47-4 is a synthetic peptide derivative specifically designed for diagnostic applications. This compound serves as a crucial substrate for the non-invasive assessment of pancreatic exocrine function. It is primarily utilized by pharmaceutical manufacturers, clinical diagnostic laboratories, and research institutions developing functional tests. Its high purity and specificity make it an essential reagent for reliable and standardized diagnostic procedures.

Application

• Pancreatic Function Testing: Primary substrate in the Bentiromide test (PABA test) for evaluating exocrine pancreatic insufficiency.
• Diagnostic Kit Manufacturing: Key raw material for the production of in-vitro diagnostic (IVD) kits and reagents.
• Clinical Research: Used in studies investigating digestive disorders, malabsorption syndromes, and pancreatic diseases.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and method validation.
• Enzyme Activity Assays: Employed in biochemical assays to measure chymotrypsin and related protease activity.

Basic Information

Product Name	Bentiromide
CAS No.	41748-47-4
Molecular Formula	C16H18N4O4
Molecular Weight	330.34 g/mol
Synonyms	N-Benzoyl-L-tyrosyl-p-aminobenzoic Acid; BT-PABA; Chymex; PABA Test Reagent; N-Benzoyl-L-Tyrosyl-4-Aminobenzoic Acid; Bentiromidum; 4-[[(2S)-2-[[(4-Aminophenyl)carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]benzoic Acid
EINECS	255-523-5

Quality Control

Our Bentiromide is manufactured under strict quality management systems. Each batch is tested to meet high-purity standards suitable for diagnostic and research use, with specifications typically referencing pharmacopeial guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to ensure traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.