Description

Ciclopirox Ethanolamine is a potent antifungal agent, specifically the ethanolamine salt of ciclopirox. This compound is valued for its broad-spectrum activity against dermatophytes, yeasts, and molds, making it a critical active pharmaceutical ingredient (API). It is primarily required by manufacturers in the pharmaceutical and personal care industries for formulating topical antifungal treatments, such as creams, solutions, and nail lacquers.

Application

• Primary Active Pharmaceutical Ingredient (API) in topical antifungal creams and ointments.
• Key component in medicated nail lacquers for the treatment of onychomycosis (fungal nail infections).
• Formulation base for dermatological solutions, lotions, and shampoos targeting dandruff and seborrheic dermatitis.
• Used in the development of veterinary antifungal products.
• Intermediate in the synthesis of other ciclopirox-based pharmaceutical derivatives.
• Research and development of novel antimicrobial formulations in academic and industrial laboratories.

Basic Information

Product Name	Ciclopirox Ethanolamine
CAS No.	41621-49-2
Molecular Formula	C12H17NO2 • C2H7NO
Molecular Weight	268.33 g/mol (Ciclopirox) + 61.08 g/mol (Ethanolamine)
Synonyms	Ciclopirox Olamine; 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone ethanolamine salt; HOE 296b; Loprox; Batrafen; Ciclopirox Ethanolamine Salt; 6-Cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one compound with 2-aminoethanol (1:1)
EINECS	Contact for details

Quality Control

Our Ciclopirox Ethanolamine is manufactured and tested to meet stringent pharmaceutical-grade standards. Quality assurance protocols include identity confirmation, purity assay, and control of specified impurities. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing results against specifications aligned with major pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm
Microbial Enumeration	Meets Ph. Eur. / USP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.