Description

Bicyclohexylammonium Fumagillin is a specialized salt form of the potent anti-angiogenic compound fumagillin, designed to enhance stability and handling properties. This high-purity intermediate is critical for the synthesis of targeted pharmaceutical agents, particularly in oncology research and development. It serves the needs of advanced pharmaceutical manufacturers and research institutions focused on developing novel therapeutics for cancer and other proliferative diseases. The compound is supplied under stringent quality controls to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel anti-cancer drugs and targeted therapies.
• Angiogenesis Inhibitor Research: Used in preclinical and research settings to study mechanisms of blood vessel formation (angiogenesis).
• API (Active Pharmaceutical Ingredient) Synthesis: Serves as a precursor in the manufacturing of finished drug substances.
• Biochemical Research: A tool compound for investigating methionine aminopeptidase 2 (MetAP2) inhibition.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for quality control and method validation.

Basic Information

Product Name	Bicyclohexylammonium Fumagillin
CAS No.	41567-78-6
Molecular Formula	C₂₆H₄₃NO₇ • C₁₂H₂₃N
Molecular Weight	Approx. 601.7 g/mol (as salt)
Synonyms	Fumagillin Bicyclohexylammonium Salt; Dicyclohexylammonium Fumagillin; Fumagillin DCHA Salt; NSC 107124; Antibiotic Fumagillin Salt; Angiogenesis Inhibitor Fumagillin Derivative; (2E,4E,6E,8E)-10-{[(2R,3S,4S,5S,6R)-5-Methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl]oxy}-10-oxodeca-2,4,6,8-tetraenoic acid compound with N,N-dicyclohexylamine
EINECS	Contact for details

Quality Control

Our Bicyclohexylammonium Fumagillin is manufactured under a strict quality management system. Every batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) documenting purity, related substances, and residual solvents is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.