Description

(3R)-3,4,5,6,9,10-Hexahydro-10-Imino-4α,5α-Bis[(Trimethylsilyl)Oxy]-3β,6β-Epoxy-2H,8H-Pyrimido[6,1-B][1,3]Oxazocin-8-One is a complex, high-purity organic intermediate featuring a unique fused heterocyclic structure with silyl-protected hydroxyl groups. This compound matters as a critical building block in advanced pharmaceutical synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) and complex natural product analogs. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries engaged in cutting-edge medicinal chemistry and process optimization.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new therapeutic agents, particularly for complex target molecules.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable synthesis of high-value target compounds.
• Academic Research: Utilized in university and institutional labs for studies in organic synthesis methodology and heterocyclic chemistry.
• Fine Chemical Synthesis: Acts as a specialized intermediate for the custom synthesis of complex, high-value organic molecules for various industrial applications.

Basic Information

Product Name	(3R)-3,4,5,6,9,10-Hexahydro-10-Imino-4α,5α-Bis[(Trimethylsilyl)Oxy]-3β,6β-Epoxy-2H,8H-Pyrimido[6,1-B][1,3]Oxazocin-8-One
CAS No.	41547-77-7
Molecular Formula	C19H33N3O5Si2
Molecular Weight	439.66 g/mol
Synonyms	4α,5α-Bis(trimethylsilyloxy)-3β,6β-epoxy-3,4,5,6,9,10-hexahydro-10-imino-2H,8H-pyrimido[6,1-b][1,3]oxazocin-8-one; Pyrimidooxazocinone derivative; TMS-protected epoxy imino lactone; CAS 41547-77-7; (3R)-Hexahydro-10-imino-4a,5a-bis(trimethylsilyloxy)-3b,6b-epoxy-2H,8H-pyrimido[6,1-b][1,3]oxazocin-8-one; Fused pyrimidine-oxazine intermediate; 41547-77-7
EINECS	Contact for details

Quality Control

Our (3R)-3,4,5,6,9,10-Hexahydro-10-Imino-4α,5α-Bis[(Trimethylsilyl)Oxy]-3β,6β-Epoxy-2H,8H-Pyrimido[6,1-B][1,3]Oxazocin-8-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with cGMP standards for use in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.