Description

2'-Deoxy-A-Uridine is a modified nucleoside analog of significant interest in biochemical and pharmaceutical research. This compound serves as a critical building block and research tool for studying nucleic acid structure, function, and metabolism. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics and diagnostic agents. Our supply of 2'-Deoxy-A-Uridine CAS NO 41546-05-8 is characterized by high purity and reliable consistency to support advanced scientific applications.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Studies: Used as a substrate or inhibitor in enzymatic assays to study the mechanisms of DNA/RNA polymerases and related enzymes.
• Antisense Oligonucleotide Synthesis: Serves as a modified monomer for the production of oligonucleotides with tailored properties for genetic research and therapeutic applications.
• Diagnostic Probe Development: Incorporated into nucleic acid probes for diagnostic assays, enhancing specificity and stability.
• Academic Research: A fundamental reagent for university and institutional labs investigating nucleic acid chemistry, epigenetics, and molecular biology pathways.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	2'-Deoxy-A-Uridine
CAS No.	41546-05-8
Molecular Formula	C9H11N3O5
Molecular Weight	241.20 g/mol
Synonyms	2'-Deoxyadenosine Uridine Analog; 2'-Deoxy-A-Urd; 9-((2R,3S,5R)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 2'-Deoxy-AU; dA-Uridine; 2'-Deoxy-A-U; Adenosine, 2'-deoxy-, 5'-(dihydrogen phosphate) (ester with uridine); 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-aminopyrimidin-2(1H)-one (related structure).
EINECS	Contact for details

Quality Control

Every batch of our 2'-Deoxy-A-Uridine is produced and tested under a strict quality management system to ensure it meets the exacting standards required for research and development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our commitment to quality and traceability ensures reliable and reproducible results for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤1.0%
Solubility	Soluble in DMSO, sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.