Description

8,5'(S)-Cycloadenosine is a chemically modified nucleoside analog of adenosine, characterized by a unique intramolecular cyclization between the ribose and adenine moieties. This structural modification imparts distinct biochemical properties, making it a valuable intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleoside chemistry, antiviral drug discovery, and the synthesis of novel therapeutic agents targeting cellular signaling pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel nucleoside-based therapeutics.
• Biochemical Research: Used as a reference standard and probe in studies of adenosine receptor interactions and enzyme kinetics.
• Antiviral Drug Discovery: Serves as a core structure for developing potential antiviral compounds.
• Academic Research: Employed in universities and research labs for studying nucleic acid chemistry and modification.
• Process Development: Used in scaling up synthetic routes for complex nucleoside analogs under GMP conditions.

Basic Information

Product Name	8,5'(S)-Cycloadenosine
CAS No.	41432-67-1
Molecular Formula	C10H11N5O3
Molecular Weight	249.23 g/mol
Synonyms	8,5'-Cycloadenosine; 8,5'-Anhydro-8-hydroxyadenosine; 8,5'-O-Cycloadenosine; 8,5'-Cyclo-adenosine; Adenosine, 8,5'-cyclo-; 8-Hydroxy-8,5'-cycloadenosine; (S)-8,5'-Cycloadenosine; 8,5'-O-Cyclo-adenosine
EINECS	Contact for details

Quality Control

Our 8,5'(S)-Cycloadenosine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom synthesis and purification to meet specific project requirements are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.