Description

(R)-1-[(2R)-1,2,3,4,4A,4Bα,5,6,7,8,10,10Aα-Dodecahydro-4β-Hydroxy-2,4Aβ,8,8-Tetramethylphenanthren-2-Yl]-1,2-Ethanediol is a high-purity, stereochemically defined intermediate of significant interest in advanced organic synthesis. Its complex, polycyclic structure with multiple chiral centers makes it a valuable building block for the development of novel, biologically active compounds. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of complex natural product analogs and steroidal frameworks.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly those with steroidal or terpenoid-like activity.
• Advanced Organic Synthesis: Serves as a sophisticated starting material or intermediate for constructing complex polycyclic molecular architectures in academic and industrial R&D.
• Natural Product Analog Synthesis: Used in the semi-synthesis or total synthesis of complex natural products and their derivatives for biological evaluation.
• Asymmetric Catalysis Research: May be employed as a substrate or ligand precursor in the development and testing of new asymmetric catalytic methodologies.
• Chemical Reference Standard: Utilized as a high-purity analytical standard for method development and quality control in related chemical processes.

Basic Information

Item	Details
Product Name	(R)-1-[(2R)-1,2,3,4,4A,4Bα,5,6,7,8,10,10Aα-Dodecahydro-4β-Hydroxy-2,4Aβ,8,8-Tetramethylphenanthren-2-Yl]-1,2-Ethanediol
CAS No.	41410-48-4
Molecular Formula	C22H38O3
Molecular Weight	350.54 g/mol
Synonyms	(2R)-2-[(1R)-1,2-Dihydroxyethyl]-4b-hydroxy-2,4a,8,8-tetramethyldodecahydrophenanthrene; (2R,4aR,4bR,10aR)-2-[(1R)-1,2-Dihydroxyethyl]-4b-hydroxy-2,4a,8,8-tetramethyldodecahydrophenanthrene; 4b-Hydroxy-2,4a,8,8-tetramethyl-2-[(1R)-1,2-dihydroxyethyl]perhydrophenanthrene; A key intermediate in the synthesis of various diterpenoids. Contact for additional aliases.
EINECS	Contact for details

Quality Control

Our (R)-1-[(2R)-1,2,3,4,4A,4Bα,5,6,7,8,10,10Aα-Dodecahydro-4β-Hydroxy-2,4Aβ,8,8-Tetramethylphenanthren-2-Yl]-1,2-Ethanediol is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. All materials are characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.