Description

Cholesterol n-Butyl Carbonate is a high-purity, functionalized sterol derivative where the 3β-hydroxyl group of cholesterol is protected as a butyl carbonate ester. This chemical modification enhances the molecule's stability and alters its solubility profile, making it a valuable intermediate for advanced synthesis. It is primarily utilized in pharmaceutical research and development, particularly in the synthesis of novel drug candidates, prodrugs, and specialized lipid-based delivery systems. This compound serves a critical role for R&D chemists and manufacturers requiring precise, high-quality sterol building blocks.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel steroidal drugs, prodrugs, and active pharmaceutical ingredients (APIs).
• Lipid Nanoparticle (LNP) Research: Used in the development and study of lipid components for advanced drug delivery systems, including mRNA vaccines and therapies.
• Bioconjugation & Prodrug Design: Serves as a linker or protective group in bioconjugation chemistry to improve drug targeting, solubility, and pharmacokinetics.
• Biomaterials & Polymer Science: A monomer or modifier for creating functional polymers with specific biocompatibility or release characteristics.
• Reference Standard: Employed as an analytical standard in quality control (QC) and research laboratories for method development and validation.
• Cosmetic & Nutraceutical R&D: Investigated for use in high-end cosmetic formulations and specialized nutraceutical products requiring modified sterols.

Basic Information

Product Name	Cholesterol n-Butyl Carbonate
CAS No.	41371-14-6
Molecular Formula	C32H54O3
Molecular Weight	486.78 g/mol
Synonyms	Cholesteryl n-Butyl Carbonate; 3β-[(Butoxycarbonyl)oxy]cholest-5-ene; Cholest-5-en-3β-ol, 3-butyl carbonate; Cholesterol Butyl Carbonate; Butyl Cholesteryl Carbonate; 5-Cholesten-3β-ol, butyl carbonate
EINECS	Contact for details

Quality Control

Our Cholesterol n-Butyl Carbonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting specifications for research and production use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.