Description

N,3,4,6-o-Tetraacetyl-α-D-Galactosaminyl Chloride is a high-purity, protected glycosyl donor essential for synthetic carbohydrate chemistry. This compound is a critical building block for the controlled synthesis of complex oligosaccharides and glycoconjugates. It is primarily utilized by research institutions and pharmaceutical companies developing novel therapeutics, diagnostics, and biological probes.

Application

• Glycosylation Reactions: As a key glycosyl donor for the stereoselective synthesis of α-linked galactosamine derivatives.
• Oligosaccharide Synthesis: A fundamental building block for constructing complex carbohydrate chains found in glycoproteins and glycolipids.
• Pharmaceutical Intermediates: Used in the research and development of carbohydrate-based drugs, including vaccines and anti-cancer agents.
• Glycoconjugate Preparation: For the chemical conjugation of carbohydrates to proteins, lipids, or other carriers to create neoglycoconjugates.
• Biochemical Research: A tool compound for studying glycosyltransferase enzymes and carbohydrate-protein interactions.
• Diagnostic Reagent Development: Serves as a precursor for labeled probes used in glycan array and lectin binding studies.

Basic Information

Product Name	N,3,4,6-o-Tetraacetyl-α-D-Galactosaminyl Chloride
CAS No.	41355-44-6
Molecular Formula	C16H22ClNO9
Molecular Weight	407.80 g/mol
Synonyms	2-(Acetylamino)-2-deoxy-α-D-galactopyranosyl Chloride 3,4,6-Triacetate; α-D-Galactosamine, N,3,4,6-tetra-O-acetyl-, chloride; 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-galactopyranosyl Chloride; Tetra-O-acetyl-α-D-galactosaminyl Chloride; Ac4αGalNAcCl; GalNAc(α1-)-Cl (Ac4); 1-Chloro-2-deoxy-3,4,6-tri-O-acetyl-2-(N-acetylamino)-α-D-galactopyranose
EINECS	Contact for details

Quality Control

Our N,3,4,6-o-Tetraacetyl-α-D-Galactosaminyl Chloride is manufactured under strict quality systems to ensure batch-to-batch consistency and high chemical purity suitable for research and process development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]D20	+100° to +120° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.