Description

1-Pyrrolidinecarbonyl Chloride, 2-Oxo- (9Ci) is a highly reactive acid chloride derivative of 2-pyrrolidone, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 2-oxopyrrolidine-1-carbonyl moiety, a key structural feature in numerous bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of complex drug candidates, including protease inhibitors and other N-heterocyclic compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides that require specific lactam-based structures.
• Peptide Mimetics & PROTACs: Facilitates the construction of peptide-like chains and linker systems for proteolysis-targeting chimeras (PROTACs).
• Polymer Chemistry: Acts as a monomer or modifying agent for creating specialized polyamides and other performance polymers.
• Material Science Research: Employed in surface functionalization and the development of novel organic frameworks and coatings.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules to study biological pathways and interactions.

Basic Information

Product Name	1-Pyrrolidinecarbonyl Chloride, 2-Oxo- (9Ci)
CAS No.	41341-01-9
Molecular Formula	C5H6ClNO2
Molecular Weight	147.56 g/mol
Synonyms	2-Oxo-1-pyrrolidinecarbonyl chloride; 1-(Chlorocarbonyl)-2-pyrrolidinone; 2-Pyrrolidone-1-carbonyl chloride; N-Carboxy-2-pyrrolidide chloride; N-(Chlorocarbonyl)-2-pyrrolidinone; 1-Pyrrolidinecarboxylic acid, 2-oxo-, chloride; 2-Oxopyrrolidine-1-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarbonyl Chloride, 2-Oxo- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to prevent moisture absorption and decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.