Description

Thymidine C5-Hydrate is a high-purity nucleoside derivative, essential for life science research and pharmaceutical development. This compound serves as a critical building block for the synthesis of oligonucleotides, modified nucleotides, and antiviral agents. It is primarily utilized by researchers and manufacturers in the biotechnology, pharmaceutical, and diagnostic industries for applications requiring precise molecular biology reagents.

Application

• Oligonucleotide Synthesis: A key phosphoramidite precursor for solid-phase synthesis of DNA and RNA strands.
• Antiviral Drug Development: Used in the research and production of nucleoside analog prodrugs, such as those targeting viral polymerases.
• Cell Culture & Media Supplement: Acts as a defined component in specialized cell culture media, particularly for selective growth conditions.
• Biochemical Research: Employed as a substrate or standard in enzymatic assays, metabolic pathway studies, and molecular biology kits.
• Diagnostic Reagent Manufacturing: Incorporated into the formulation of reagents for PCR, sequencing, and other molecular diagnostic techniques.
• Reference Standard: Serves as a high-purity analytical standard for quality control in pharmaceutical and research laboratories.

Basic Information

Product Name	Thymidine C5-Hydrate
CAS No.	41308-58-1
Molecular Formula	C10H14N2O5 • xH2O
Molecular Weight	242.23 g/mol (Anhydrous basis)
Synonyms	1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil Hydrate; 2'-Deoxythymidine Hydrate; 5-Methyldeoxyuridine Hydrate; dT Hydrate; Thymidine 5-Hydrate; Thymine Deoxyriboside Hydrate; NSC 21548 (Hydrate); Deoxythymidine Hydrate
EINECS	Contact for details

Quality Control

Our Thymidine C5-Hydrate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and LOD/KF for water content, to ensure it meets the stringent requirements for research and pharmaceutical use. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	As per hydrate specification (e.g., 5-10%)
Related Substances (HPLC)	Total impurities ≤2.0%
Specific Rotation	Contact for details
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.