Description

3-Methylbenzo[B]Thiophene-2-Carbonyl Chloride is a versatile and highly reactive acyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the 3-methylbenzothiophene-2-carbonyl moiety, a key structural motif in the development of high-value functional materials and active pharmaceutical ingredients (APIs). This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries who require a reliable, high-purity intermediate for constructing complex heterocyclic systems.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Building block for creating organic semiconductors, liquid crystals, and advanced polymers with specific electronic or photophysical properties.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes and molecular tags for studying biological processes.
• Dye and Pigment Manufacturing: Intermediate for synthesizing specialized heterocyclic dyes and organic pigments.
• Custom Synthesis & Contract Manufacturing: A crucial reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Methylbenzo[B]Thiophene-2-Carbonyl Chloride
CAS No.	41280-76-6
Molecular Formula	C11H7ClOS
Molecular Weight	222.69 g/mol
Synonyms	3-Methylbenzo[b]thiophene-2-carbonyl chloride; 2-(Chlorocarbonyl)-3-methylbenzo[b]thiophene; 3-Methyl-2-benzothiophenecarbonyl chloride; 3-Methylbenzo[b]thien-2-yl carbonyl chloride; 3-Methyl-1-benzothiophene-2-carbonyl chloride; 3-Methylbenzothiophene-2-carbonyl chloride; 2-Carboxy-3-methylbenzothiophene chloride
EINECS	Contact for details

Quality Control

Our 3-Methylbenzo[B]Thiophene-2-Carbonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and maintain product integrity. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.