Description

1H-Tetrazole-1-Acetyl Chloride is a high-value, reactive chemical intermediate essential for the synthesis of complex heterocyclic compounds. This compound matters for its role as a key building block in the development of active pharmaceutical ingredients (APIs), particularly in the creation of tetrazole-containing drugs. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for advanced synthesis and process development.

Application

• Pharmaceutical Synthesis: A critical precursor in the production of tetrazole-based active pharmaceutical ingredients (APIs), including sartans and other cardiovascular drugs.
• Agrochemical Intermediates: Used in the research and manufacturing of novel herbicides, fungicides, and insecticides that incorporate the tetrazole moiety.
• Peptide Chemistry: Serves as a coupling agent or protecting group reagent in the synthesis of modified peptides and peptidomimetics.
• Material Science Research: Employed in the development of high-energy materials, polymers, and ligands for metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of bio-conjugation reagents and molecular probes for biochemical research.

Basic Information

Product Name	1H-Tetrazole-1-Acetyl Chloride
CAS No.	41223-92-1
Molecular Formula	C3H3ClN4O
Molecular Weight	146.53 g/mol
Synonyms	1H-Tetrazole-1-acetyl chloride; Tetrazol-1-ylacetyl chloride; 1-(Chloroacetyl)tetrazole; 1-(Chloroformylmethyl)-1H-tetrazole; 1H-Tetrazol-1-ylacetyl chloride; 1-Tetrazolylacetyl chloride; (1H-Tetrazol-1-yl)acetyl chloride; Acetyl chloride, (1H-tetrazol-1-yl)-
EINECS	Contact for details

Quality Control

Our 1H-Tetrazole-1-Acetyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.