Description

n-Methylbenzimidoyl Bromide is a versatile and reactive benzimidoyl halide intermediate of significant importance in advanced organic synthesis. Its primary value lies in its role as a key building block for constructing complex nitrogen-containing heterocycles and pharmaceutical scaffolds. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various benzimidazole and benzimidazole-derived drug candidates, including potential antivirals, antifungals, and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of novel fungicides, herbicides, and plant growth regulators that require the benzimidazole pharmacophore.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized N-donor ligands used in coordination chemistry and homogeneous catalysis.
• Material Science Research: Employed in the creation of organic semiconductors, photoactive compounds, and other functional organic materials.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic and R&D Laboratories: Used in methodological development and exploratory research for new synthetic transformations involving C-N bond formation.

Basic Information

Product Name	n-Methylbenzimidoyl Bromide
CAS No.	41182-85-8
Molecular Formula	C8H8BrN
Molecular Weight	198.06 g/mol
Synonyms	N-Methylbenzimidoyl Bromide; 1-Methyl-1H-benzimidazole-2-carbonyl bromide; Benzimidoyl Bromide, N-Methyl-; 2-Bromo-N-methyl-1H-benzimidazole-1-carboxamide (tautomeric form); Methylbenzimidoyl Bromide; N-Methyl-α-bromobenzimidamide; 41182-85-8; N-Methyl benzimidoyl bromide
EINECS	Contact for details

Quality Control

Our n-Methylbenzimidoyl Bromide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data to support your R&D and scale-up activities. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each batch and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. The compound is light-sensitive (store away from light). Keep container tightly sealed under an inert atmosphere if possible to minimize degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.