Description

4-Chloro-1-(4-Fluorophenyl)Butan-1-One is a versatile and high-purity organic building block, specifically a fluorinated and chlorinated aromatic ketone. Its bifunctional halogenated structure makes it a critical intermediate for synthesizing complex molecules in advanced research and development. This compound is essential for pharmaceutical chemists, agrochemical researchers, and material scientists seeking to introduce specific halogenated motifs into target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorophenyl and chlorobutyl pharmacophores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides where its halogenated structure contributes to biological activity.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic electronic materials due to its aromatic core and halogen substituents.
• Organic Synthesis & Catalysis Research: Employed in cross-coupling reactions, Grignard reactions, and as a substrate for exploring new halogenation or dehalogenation methodologies.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom chemical synthesis services targeting specialized, high-value fine chemicals.

Basic Information

Product Name	4-Chloro-1-(4-Fluorophenyl)Butan-1-One
CAS No.	41167-07-1
Molecular Formula	C10H10ClFO
Molecular Weight	200.64 g/mol
Synonyms	1-(4-Fluorophenyl)-4-chlorobutan-1-one; 4'-Fluloro-4-chlorobutyrophenone; p-Fluorophenacyl chloride; 4-Chloro-1-(p-fluorophenyl)-1-butanone; 4-Chloro-4'-fluorobutyrophenone; γ-Chloro-p-fluorobutyrophenone; 4-Chlorobutyl 4-fluorophenyl ketone
EINECS	Contact for details

Quality Control

Our 4-Chloro-1-(4-Fluorophenyl)Butan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in GMP-aligned synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.