Description

2,3,4,6-Tetra-o-Acetyl-β-D-Galactopyranosyl Isothiocyanate is a key protected glycosyl donor and building block in synthetic carbohydrate chemistry. This compound is essential for the efficient and stereoselective synthesis of thioglycosides and glycoconjugates, which are critical for biological research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for creating novel glycoprobes, glycomimetics, and therapeutic agents.

Application

• Glycoconjugate Synthesis: A crucial reagent for the preparation of thioglycoside-linked glycoconjugates, including glycoproteins and glycolipids.
• Pharmaceutical Intermediates: Serves as a vital building block in the synthesis of carbohydrate-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Probes: Used to create labeled glycans and probes for studying carbohydrate-protein interactions, enzyme mechanisms, and cell surface recognition.
• Diagnostic Reagent Development: Employed in the manufacture of diagnostic tools and assays that target specific carbohydrate antigens.
• Glycomimetics Research: Facilitates the development of glycomimetic compounds for therapeutic applications in immunology and oncology.
• Oligosaccharide Assembly: An important donor in automated and manual solid-phase or solution-phase oligosaccharide synthesis.

Basic Information

Product Name	2,3,4,6-Tetra-o-Acetyl-β-D-Galactopyranosyl Isothiocyanate
CAS No.	41135-18-6
Molecular Formula	C15H19NO9S
Molecular Weight	389.38 g/mol
Synonyms	2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosyl isothiocyanate; 1-Isothiocyanato-2,3,4,6-tetra-O-acetyl-β-D-galactopyranose; β-D-Galactopyranosyl isothiocyanate, tetraacetate; Tetra-O-acetyl-β-D-galactopyranosyl isothiocyanate; Galactose tetraacetate isothiocyanate; 2,3,4,6-Tetra-O-acetyl-1-isothiocyanato-β-D-galactopyranose; Ac4Galβ-NCS
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetra-o-Acetyl-β-D-Galactopyranosyl Isothiocyanate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and production. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated pharmaceutical and biotech applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation [α]²⁰D	Contact for details
Solubility	Soluble in common organic solvents (e.g., DCM, DMF, Acetone)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.