Description

5-Fluoro-2',3'-Dideoxy-3'-Fluorouridine is a fluorinated nucleoside analog with significant research and pharmaceutical interest. This compound matters as a key intermediate in the synthesis of novel antiviral and anticancer agents, particularly in the development of modified nucleoside therapeutics. Pharmaceutical R&D laboratories, biotechnology companies, and advanced chemical synthesis units require this high-purity building block for their drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Antiviral Research: Used in the development of potential therapeutics targeting viral polymerases and reverse transcriptases.
• Oncology Research: Investigated as a precursor for antimetabolite drugs designed to inhibit cancer cell proliferation.
• Biochemical Tool: Serves as a substrate or inhibitor in enzymatic studies to understand nucleic acid metabolism.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Process Chemistry: Used in scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	5-Fluoro-2',3'-Dideoxy-3'-Fluorouridine
CAS No.	41107-55-5
Molecular Formula	C9H10F2N2O4
Molecular Weight	248.18 g/mol
Synonyms	5-Fluoro-2',3'-dideoxy-3'-fluorouridine; 2',3'-Dideoxy-5-fluoro-3'-fluorouridine; 5-Fluoro-3'-fluoro-2',3'-dideoxyuridine; 3'-F-5-F-ddU; 5-F-3'-F-ddU; 2',3'-Dideoxy-3'-fluoro-5-fluorouridine; Fd4FU; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2',3'-Dideoxy-3'-Fluorouridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Quality is verified through comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.