Description

S-(2-Hydroxy-5-Nitrobenzyl)-6-Thioguanosine is a chemically modified nucleoside derivative, specifically a thioguanosine analog, of significant interest in biochemical and pharmaceutical research. This compound matters as a valuable tool for studying nucleic acid structure, enzyme mechanisms, and as a potential precursor in the development of novel therapeutic agents. It is primarily needed by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in nucleoside chemistry, antiviral research, and the synthesis of modified biomolecules.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving purine metabolism and nucleoside-processing enzymes.
• Pharmaceutical R&D: Serves as a key intermediate or building block in the synthesis of novel nucleoside-based drug candidates, including potential antiviral or anticancer agents.
• Nucleic Acid Chemistry: Employed in the study of RNA structure and function, and in the development of chemically modified oligonucleotides for diagnostic or therapeutic applications.
• Probe Development: Can be utilized to create fluorescent or affinity-labeled probes for detecting specific biological interactions or cellular processes.
• Academic Research: A critical reagent for universities and research institutes exploring the chemical biology of nucleosides and their role in cellular signaling.

Basic Information

Product Name	S-(2-Hydroxy-5-Nitrobenzyl)-6-Thioguanosine
CAS No.	41094-07-9
Molecular Formula	C₁₇H₁₈N₆O₇S
Molecular Weight	450.43 g/mol
Synonyms	6-Thioguanosine, S-(2-Hydroxy-5-nitrobenzyl) derivative; 6-Mercaptoguanosine, S-(2-Hydroxy-5-nitrobenzyl) derivative; 9-β-D-Ribofuranosyl-6-[[(2-hydroxy-5-nitrophenyl)methyl]thio]-9H-purin-2-amine; 6-[[(2-Hydroxy-5-nitrophenyl)methyl]thio]guanosine; S-(2-Hydroxy-5-nitrobenzyl)-6-mercaptoguanosine; 6-S-(2-Hydroxy-5-nitrobenzyl)thioguanosine
EINECS	Contact for details

Quality Control

Our S-(2-Hydroxy-5-Nitrobenzyl)-6-Thioguanosine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization. A Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment to guarantee traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystalline solid
Identification (HPLC / MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.