Description

Pseudomonic Acid I is a key intermediate and active pharmaceutical ingredient (API) belonging to the class of monic acid antibiotics. This compound is of significant commercial and research interest due to its role as a precursor in the synthesis of mupirocin, a potent topical antibiotic widely used in clinical settings. It is primarily sought by pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in the development and production of anti-infective agents. The material is supplied to meet the stringent quality requirements of these demanding applications.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the chemical synthesis of the antibiotic Mupirocin (Bactroban®).
• Active Pharmaceutical Ingredient (API): Serves as the core active component in formulated antibiotic preparations for topical use.
• Antimicrobial Research: Used in biochemical and microbiological research to study antibiotic mechanisms of action and bacterial resistance.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, or NMR method development and validation.
• Veterinary Medicine: Utilized in the development of topical antimicrobial treatments for animal healthcare.
• Fine Chemical Synthesis: Acts as a starting material or intermediate for the synthesis of novel antibiotic analogs and derivatives in medicinal chemistry.

Basic Information

Product Name	Pseudomonic Acid I
CAS No.	40980-51-6
Molecular Formula	C26H44O9
Molecular Weight	500.63 g/mol
Synonyms	Monic Acid A; (E)-4-[(2S,3R,4R,5S)-5-[(2S,3S,4S,5S)-2,3-Epoxy-5-hydroxy-4-methylhexyl]tetrahydro-3,4-dihydroxy-2-furanyl]-3-methyl-2-butenoic acid; 9-Hydroxynonanoic Acid Derivative; Antibiotic Pseudomonic Acid A; Mupirocin Intermediate; BA-TC 1901
EINECS	Contact for details

Quality Control

Our Pseudomonic Acid I is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, aligning with pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) providing results for assay, related substances, residual solvents, and microbiological tests is supplied with every shipment. We support compliance with cGMP, ICH Q7, and other relevant regulatory guidelines for API production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Microbial Limits	Meets Ph. Eur./USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.