Description

1-Azido-1-Cyclooctene is a specialized, high-energy organic azide compound that serves as a versatile building block in advanced chemical synthesis. Its unique strained-ring structure and reactive azide functional group make it a critical precursor for click chemistry, particularly in Huisgen 1,3-dipolar cycloaddition reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors who require precise, modular methods for constructing complex molecular architectures, such as bioconjugates, polymers, and novel heterocyclic compounds.

Application

• Click Chemistry Reagent: A key precursor for copper-catalyzed azide-alkyne cycloaddition (CuAAC) to create 1,2,3-triazole linkages in drug discovery and bioconjugation.
• Pharmaceutical Intermediate: Used in the synthesis of novel active pharmaceutical ingredients (APIs) and prodrugs, leveraging its strained alkene and azide for selective transformations.
• Polymer & Materials Science: Serves as a functional monomer or cross-linking agent for creating advanced polymers with tailored properties, including smart materials and hydrogels.
• Agrochemical Synthesis: Employed in the research and development of new herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Facilitates the labeling and study of biomolecules (proteins, nucleic acids) through bioorthogonal chemistry techniques.
• Energetic Materials Research: Investigated as a component in the development of novel high-energy-density materials (HEDMs) due to its azide functionality.

Basic Information

Product Name	1-Azido-1-Cyclooctene
CAS No.	40934-24-5
Molecular Formula	C8H13N3
Molecular Weight	151.21 g/mol
Synonyms	1-Azidocyclooct-1-ene; Cyclooct-1-en-1-yl azide; 1-Cyclooctenyl azide; Azidocyclooctene; 1-N3-Cyclooctene
EINECS	Contact for details

Quality Control

Our 1-Azido-1-Cyclooctene is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We adhere to cGMP principles where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to the light-sensitive and potentially shock-sensitive nature of organic azides, handle and store with appropriate precautions. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.