Description

2-(4-Chlorophenyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing quinoline-based scaffolds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting specific receptor sites.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with quinoline core structures.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced organic electronic materials and metal-organic frameworks (MOFs).
• Dye & Pigment Manufacturing: Acts as an intermediate for producing specialized quinoline-based dyes and colorants.
• Ligand Synthesis: Utilized for creating complex chelating ligands used in catalysis and metal extraction processes.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	2-(4-Chlorophenyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride
CAS No.	40846-25-1
Molecular Formula	C19H15Cl2NO
Molecular Weight	344.24 g/mol
Synonyms	4-Chlorobenzoyl-6,8-dimethylquinoline; 6,8-Dimethyl-2-(4-chlorophenyl)quinoline-4-carbonyl chloride; 2-(p-Chlorophenyl)-6,8-dimethyl-4-quinolinecarbonyl chloride; Quinoline-4-carbonyl chloride, 2-(4-chlorophenyl)-6,8-dimethyl-; 40846-25-1; 2-(4-Chlorophenyl)-6,8-dimethyl-4-quinolinecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Chlorophenyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.