Description

3'-Deoxytubercidin is a synthetic nucleoside analog and a derivative of the natural product tubercidin. This compound is a valuable biochemical tool and research chemical, primarily utilized for its ability to inhibit specific cellular processes. It is of significant interest to researchers in the fields of molecular biology, enzymology, and medicinal chemistry. The material is supplied as a high-purity standard to support critical R&D and analytical applications.

Application

• Biochemical Research: Used as a substrate analog to study the mechanisms of nucleoside-metabolizing enzymes, including kinases and phosphorylases.
• Enzyme Inhibition Studies: Serves as a potent inhibitor in assays targeting adenosine kinase and other purine salvage pathway enzymes.
• Antiviral and Anticancer Research: Investigated for its potential biological activity in preliminary screening studies for novel therapeutic agents.
• Cell Biology: Employed to modulate intracellular nucleotide pools and study the effects on cell proliferation and apoptosis.
• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and analytical method development in drug discovery.
• Academic Research: A key reagent for universities and research institutes exploring nucleotide chemistry and signal transduction pathways.

Basic Information

Product Name	3'-Deoxytubercidin
CAS No.	40725-89-1
Molecular Formula	C11H14N4O3
Molecular Weight	250.25 g/mol
Synonyms	7-Deaza-3'-deoxyadenosine; 4-Amino-7-(3-deoxy-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; 3'-Deoxy-7-deazaadenosine; NSC 154020; Tubercidin 3'-deoxy derivative; 3'-dTub
EINECS	Contact for details

Quality Control

Every batch of 3'-Deoxytubercidin is manufactured under a strict quality management system. The product undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with research-grade specifications. We support cGMP and ISO 9001 standards for consistent quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or refrigerated (2-8°C) for long-term stability. This material is hygroscopic (moisture-sensitive); the container must be kept in a dry environment and sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.