Description

4-Amino-6-Chloro-1--D-Ribofuranosylimidazo[4,5-C]Pyridine is a sophisticated nucleoside analog with a fused imidazopyridine core structure. This compound is of significant interest in pharmaceutical research and development, particularly as a key intermediate or building block for novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of nucleoside-based drugs, antivirals, and other bioactive molecules. The specific structural features of this molecule make it a valuable scaffold for probing biological mechanisms and developing targeted treatments.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel nucleoside analog drugs.
• Antiviral Research: Investigated for its potential as a precursor in the development of antiviral agents targeting viral polymerases.
• Oncology Drug Discovery: Used in research programs focused on creating targeted cancer therapies that interfere with DNA/RNA synthesis.
• Biochemical Tool Compound: Employed in enzymatic studies and as a probe to understand cellular nucleotide metabolism pathways.
• Organic Synthesis: Acts as a specialized starting material for medicinal chemists to create libraries of compounds for high-throughput screening.

Basic Information

Product Name	4-Amino-6-Chloro-1--D-Ribofuranosylimidazo[4,5-C]Pyridine
CAS No.	40656-71-1
Molecular Formula	C11H13ClN4O4
Molecular Weight	300.70 g/mol
Synonyms	4-Amino-6-chloro-1-β-D-ribofuranosylimidazo[4,5-c]pyridine; 6-Chloro-1-(β-D-ribofuranosyl)imidazo[4,5-c]pyridin-4-amine; 4-Amino-6-chloro-1-(β-D-ribofuranosyl)-1H-imidazo[4,5-c]pyridine; 1-(β-D-Ribofuranosyl)-4-amino-6-chloroimidazo[4,5-c]pyridine; 4-Amino-6-chloro-1-ribofuranosylimidazo[4,5-c]pyridine; Imidazo[4,5-c]pyridine nucleoside derivative
EINECS	Contact for details

Quality Control

Our 4-Amino-6-Chloro-1--D-Ribofuranosylimidazo[4,5-C]Pyridine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.