Description

2-Acetoxy-2-Methylpropionyl Bromide is a specialized acyl bromide derivative, a high-purity reagent crucial for advanced organic synthesis. This compound matters as a versatile and reactive building block for introducing functionalized acyl groups under controlled conditions. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing protected carboxylic acid functionalities.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific acyl moieties.
• Polymer Chemistry: Serves as a functional monomer or chain transfer agent in the synthesis of specialty polymers with tailored properties.
• Peptide & Protein Modification: Employed for selective acylation reactions in bioconjugation and the development of peptide-based therapeutics.
• Material Science Research: Utilized in surface functionalization and the creation of novel organic-inorganic hybrid materials.
• Cross-Coupling Reagent: Acts as an electrophile in metal-catalyzed cross-coupling reactions to form carbon-carbon bonds.

Basic Information

Product Name	2-Acetoxy-2-Methylpropionyl Bromide
CAS No.	40635-67-4
Molecular Formula	C7H11BrO3
Molecular Weight	223.07 g/mol
Synonyms	2-(Acetyloxy)-2-methylpropanoyl Bromide; α-Acetoxyisobutyryl Bromide; 2-Methyl-2-(acetyloxy)propanoyl Bromide; Acetoxy Pivaloyl Bromide; Bromide of Acetoxy Pivalic Acid; 2-Acetoxy-2-methylpropanoic Acid Bromide; 2-Acetoxyisobutyryl Bromide
EINECS	Contact for details

Quality Control

Our 2-Acetoxy-2-Methylpropionyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and titration to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Impurities (HPLC)	≤ 2.0% (total)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.