Description

(3-Nitrophenoxy)Acetyl Chloride is a specialized organic intermediate featuring a reactive acid chloride group and a nitro-substituted aromatic ring. This compound matters as a key building block for synthesizing more complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing phenoxyacetyl derivatives.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Synthesis: Used in the production of advanced herbicides and plant growth regulators that require a phenoxyacetyl backbone.
• Peptide Mimetics & Conjugation: Serves as an acylating agent for modifying amino acids or peptides to create mimetics or drug conjugates.
• Ligand & Catalyst Development: Employed in research to create specialized ligands for metal complexes or organocatalysts.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for introducing nitro-phenoxy groups into polymer chains to alter material properties.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex organic dyes and pigments where the nitro group influences color and stability.

Basic Information

Product Name	(3-Nitrophenoxy)Acetyl Chloride
CAS No.	40257-02-1
Molecular Formula	C8H6ClNO4
Molecular Weight	215.59 g/mol
Synonyms	2-(3-Nitrophenoxy)acetyl chloride; 3-Nitrophenoxyacetyl chloride; Acetyl chloride, 2-(3-nitrophenoxy)-; (3-Nitro-phenoxy)-acetyl chloride; NSC 163082; 3-Nitrophenoxyacetic acid chloride; α-Chloro-3-nitrophenoxyacetone (common misnomer); m-Nitrophenoxyacetyl chloride
EINECS	Contact for details

Quality Control

Our (3-Nitrophenoxy)Acetyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at 2-8°C under an inert atmosphere. Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed and handled under dry conditions to prevent decomposition. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.