Description

2-(Benzylthio)-4-Chlorobenzoic Acid Chloride is a specialized organic intermediate featuring a reactive acid chloride group and a benzylthio substituent. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical and active pharmaceutical ingredient (API) manufacturing sectors.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides, leveraging its chlorinated aromatic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptide Mimetics and Conjugation: The acid chloride functionality enables efficient amide bond formation for creating peptide analogs or conjugating molecules to carriers.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties.
• Custom Synthesis and Contract Manufacturing: A key requested compound for bespoke synthesis projects in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	2-(Benzylthio)-4-Chlorobenzoic Acid Chloride
CAS No.	40183-55-9
Molecular Formula	C14H10Cl2OS
Molecular Weight	297.20 g/mol
Synonyms	4-Chloro-2-(phenylmethylthio)benzoyl chloride; 2-(Benzylsulfanyl)-4-chlorobenzoyl chloride; Benzoic acid, 4-chloro-2-[(phenylmethyl)thio]-, chloride; 4-Chloro-2-(benzylthio)benzoyl chloride; 2-(Benzylthio)-4-chlorobenzoyl chloride; α-Chloro-4-chloro-2-(benzylthio)benzaldehyde (obsolete); 40183-55-9
EINECS	Contact for details

Quality Control

Every batch of 2-(Benzylthio)-4-Chlorobenzoic Acid Chloride is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from strong bases, oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.