Description

Se-(p-Nitrobenzyl)-6-Seleno-Inosine is a specialized organoselenium nucleoside derivative, a key intermediate in advanced biochemical research and pharmaceutical development. This compound is valued for its unique selenium incorporation, which imparts distinct chemical and biological properties compared to its sulfur or oxygen analogs. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel nucleoside analogs, enzyme inhibitors, and probes for studying selenoprotein function and nucleic acid chemistry.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel antiviral and anticancer nucleoside prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving purine nucleoside phosphorylases or other nucleoside-metabolizing enzymes.
• Probe Development: Serves as a precursor for developing selenium-labeled probes for X-ray crystallography or other structural biology techniques.
• Selenoprotein Mimetics: Employed in the research and development of synthetic mimics of naturally occurring selenoproteins for therapeutic applications.
• Chemical Biology Tool: Utilized to study the role of selenium in redox biology and nucleic acid modification.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	Se-(p-Nitrobenzyl)-6-Seleno-Inosine
CAS No.	40144-12-5
Molecular Formula	C16H15N5O6Se
Molecular Weight	460.29 g/mol
Synonyms	6-[(4-Nitrobenzyl)seleno]-9-β-D-ribofuranosyl-9H-purine; 6-(p-Nitrobenzylseleno)inosine; 6-[(4-Nitrobenzyl)selanyl]-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purine; p-Nitrobenzyl 6-selenoinosine; Se-(4-Nitrobenzyl)-6-selenoinosine; 6-(4-Nitrobenzylseleno)purine riboside
EINECS	Contact for details

Quality Control

Our Se-(p-Nitrobenzyl)-6-Seleno-Inosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and elemental analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.