Description

Ethyl 3-Azidopropanoate is a versatile bifunctional organic compound featuring both an azide group and an ester moiety. This unique structure makes it a valuable building block for click chemistry, particularly in the synthesis of complex molecules via the copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for applications ranging from drug discovery to polymer modification.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of triazole-containing active pharmaceutical ingredients (APIs) and prodrugs via click chemistry.
• Bioconjugation & Probe Synthesis: Used for labeling biomolecules (proteins, peptides, nucleic acids) with fluorescent dyes, affinity tags, or other functional groups.
• Polymer & Materials Science: Serves as a monomer or cross-linking agent for creating functional polymers, hydrogels, and smart materials with tailored properties.
• Agrochemical Research: Employed in the design and synthesis of novel crop protection agents and herbicides.
• Chemical Biology: Facilitates activity-based protein profiling (ABPP) and the study of biological pathways through bioorthogonal chemistry.
• Library Synthesis: Enables high-throughput combinatorial chemistry for rapid generation of diverse compound libraries in drug discovery.

Basic Information

Product Name	Ethyl 3-Azidopropanoate
CAS No.	40139-55-7
Molecular Formula	C5H9N3O2
Molecular Weight	143.14 g/mol
Synonyms	3-Azidopropionic Acid Ethyl Ester; Ethyl 3-Azidopropionate; Azidopropionic Acid Ethyl Ester; Ethyl β-Azidopropionate; 40139-55-7; NSC 334365; Azidoethyl Propionate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Azidopropanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR), to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials. Due to the presence of an organic azide group, handle and store in accordance with safe laboratory practices for azide compounds.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.